Intracellular signaling pathways act as the major transducers of information within the cell. Understanding and manipulating these pathways is the focus of network engineering (sometimes called systems biology). Network engineering often involves a combination of experimental and computational approaches to explore the connections between molecules in complex reaction networks, such as those involved in metabolism.
Metabolic control of persister formation in Escherichia coli (Molecular Cell)
Princeton University’s core faculty members in this area: